Rusev, Rostislav Pavlov; Русев, Ростислав Павлов; Atanasov, Boris; Атанасов, Борис; Takov, Tihomir Borisov; Таков, Тихомир Борисов; Hristov, Marin Hristov; Христов, Марин Христов
Microelectronic networks analogous to protein hydrogen bonded networks made from backbone peptides and water molecules
2008
Proceedings of the Technical University – Sofia, 58(2), 2008, pp. 29-299
Технически университет - София
1311-0829 [issn]
Article
eng
microelectronics, proton transfer, hydrogen bond, single-electron transistor
For microelectronic purposes, signal transfer (proton transfer) in a hydrogen bonding network is studied. The network is extracted from β-lactamase and it includes atoms from protein backbone and water molecules. The model of proton transfer in hydrogen bonds is developed on the basis of Marcus theory and the protein electrostatic theory. The investigations show that the haracteristics of hydrogen bonds are similar to V-A characteristics of single-electron transistor, semiconductor diode and current generator. The entire network is similar to a microelectronic circuit with two inputs and two outputs. In addition, it can be used for a signal transfer.
Reviewer prof. Elisaveta Gadjeva. - Formulas, diags. - References, pp. 299